386
Participants
Start Date
August 4, 2025
Primary Completion Date
February 1, 2032
Study Completion Date
August 1, 2032
Home Based Exercise
This is a six month intervention where participants will walk at home for exercise with guidance from a study coach. They will attend two to four weekly meetings with the coach at the clinical site in the first 4 weeks following randomization, followed by once weekly telephone coaching calls for the remainder of the six-month intervention
Nitrate Rich Beetroot Juice
Participants will drink one shot of nitrate rich beet-root juice twice daily for six months.
Attention Control
"Participants will be asked to participate in weekly meetings with the coach in the attention control group for weeks 1-26. A staff member will present a topic from the National Institute on Aging age pages relevant to health, such as cancer screening or blood pressure treatment. Calls will last approximately 5-15 minutes and will focus on educational topics such as diabetes, healthy eating, and Medicare Part D."
Placebo Beetroot Juice Without Nitrate
Participants will drink one shot of placebo beetroot without nitrate juice twice daily for six months.
NOT_YET_RECRUITING
University of Pittsburgh, Pittsburgh
NOT_YET_RECRUITING
Emory University School of Medicine, Atlanta
RECRUITING
Northwestern University Feinberg School of Medicine, Chicago
RECRUITING
University of Chicago, Chicago
NOT_YET_RECRUITING
University of Arizona, Tucson
RECRUITING
Rancho Research Institute, Downey
NOT_YET_RECRUITING
Dartmouth Hitchcock Medical Center, Lebanon
Rancho Research Institute
UNKNOWN
University of Chicago
OTHER
Wake Forest University
OTHER
University of Pittsburgh Medical Center
OTHER
Emory University
OTHER
University of Arizona
OTHER
Dartmouth-Hitchcock Medical Center
OTHER
Northwestern University
OTHER