Study of Dalpiciclib Isethionate Plus Pyrotinib Maleate in the Treatment of Advanced Esophageal Squamous Cell Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

November 1, 2024

Primary Completion Date

October 30, 2025

Study Completion Date

October 30, 2027

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
DRUG

Dalpiciclib + Pyrotinib

Dalpiciclib Isethionate tablets, 125mg, oral administration on days 1 to 21, followed by a 7-day drug holiday, every 4 weeks; Pyrotinib Maleate tablets, 320mg, oral administration once daily on days 1 to 28, every 4 weeks; Treatment will continue until disease progression, intolerable toxicity, initiation of new antitumor therapy, withdrawal of informed consent, or the investigator determines that the subject should discontinue study treatment.

Trial Locations (1)

100142

RECRUITING

Department of GI Oncology, Peking University Cancer Hospital,, Beijing

All Listed Sponsors
lead

Peking University

OTHER