24
Participants
Start Date
July 21, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
February 28, 2028
Reparative Autologous peripheral nerve tissue
"At the time participants are receiving the standard of care deep brain stimulation (DBS) surgery, a standard incision on the lateral aspect near the ankle is made, the sural nerve is identified, an about 3 cm biopsy of the sural nerve is obtained and the incision is closed.~From the biopsied section, the epineurium is removed, fascicles are cut, and (\~5 pieces per side; \~ 5mm length x 1.5 mm diameter: approximately 10 cubic millimeters) implanted bilaterally into the nucleus basalis of Meynert (NBM) or substantia nigra (SN)."
RECRUITING
University of Kentucky, Lexington
National Institute on Aging (NIA)
NIH
Craig van Horne, MD, PhD
OTHER