200
Participants
Start Date
May 1, 2025
Primary Completion Date
March 31, 2028
Study Completion Date
June 30, 2028
RETRIAL-MH
Participants will complete: daily diaries for 6 weeks, from about 2 weeks prior to starting VTD to about 4 weeks after; biweekly surveys, from about 2 weeks prior to starting VTD to 6 months after, and 2 quarterly surveys (at 9mo and 12mo post-initiation of VTD).
RETRIAL-Liver
Participants may have a research liver function test done prior to starting VTD and 28 days after, if not done clinically.
RETRIAL-Neuro
participants will complete a neurocognitive assessment prior to starting VTD and 28 days after.
University of Pittsburgh Medical Center, Pittsburgh
Nemours Children's, Wilmington
Johns Hopkins University, Baltimore
Emory University, Atlanta
Nemours Children's, Jacksonville
Nemours Children's, Pensacola
Nemours Children's, Orlando
Indiana University, Bloomington
University of Michigan, Ann Arbor
Washington University at St. Louis, St Louis
Kansas University Medical Center, Kansas City
University of Texas Southwestern Medical Center, Dallas
Children's Hospital Colorado, Aurora
National Jewish Health, Denver
Seattle Children's Hospital, Seattle
Massachusetts General Hospital, Boston
Boston Children's Hospital, Boston
Cystic Fibrosis Foundation
OTHER
Johns Hopkins University
OTHER
Massachusetts General Hospital
OTHER
National Jewish Health
OTHER
Indiana University
OTHER
Children's Hospital Colorado
OTHER
University of Kansas Medical Center
OTHER
Washington University School of Medicine
OTHER
Boston Children's Hospital
OTHER