Lorlatinib as Neoadjuvant Treatment in Stage IB-IIIB ALK-rearranged Non-Small Cell Lung Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

November 15, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

May 31, 2027

Conditions
Neoadjuvant Non-Small Cell Lung Cancer
Interventions
DRUG

Lorlatinib 100 mg

Eligible patients will be registered to receive oral lorlatinib 100mg qd for 6-8 weeks each during the neoadjuvant therapy phase

All Listed Sponsors
collaborator

Hunan Cancer Hospital

OTHER

collaborator

Liaoning Cancer Hospital & Institute

OTHER

collaborator

Air Force Military Medical University, China

OTHER

collaborator

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

lead

Peking University People's Hospital

OTHER

NCT06682884 - Lorlatinib as Neoadjuvant Treatment in Stage IB-IIIB ALK-rearranged Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter