A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

740

Participants

Timeline

Start Date

December 31, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

July 31, 2030

Conditions
Hepatocellular Carcinoma (HCC)
Interventions
DRUG

TPST-1120

TPST-1120 is an orally administered competitive antagonist of peroxisome proliferator-activated receptor α (PPARα)

BIOLOGICAL

Atezolizumab

Atezolizumab is an IV administered biologic.

BIOLOGICAL

Bevacizumab

Bevacizumab is an IV administered biologic.

Sponsors
All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Tempest Therapeutics

INDUSTRY