Polaprezinc (Zinc L-carnosine) in Infants With Gastroesophageal Reflux

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

April 1, 2025

Study Completion Date

July 1, 2025

Conditions
Gastroesophageal Reflux (GER)Infants
Interventions
DEVICE

Zinc-L carnosine/Polaprezinc

This will be a randomised, single blind, controlled, multicenter study, designed to evaluate efficacy and safety of Zinc-L carnosine/Polaprezinc in infants (1-12 months of age) with symptoms suggestive of GER. This study will include a 2-week screening period, and a 8-week treatment period. After the screeing phase, eligible patients will be randomly assigned to either Zinc-L carnosine/Polaprezinc (Hepilor Liquido, Azienda Farmaceutica Italiana, Italy) twice a day or thickened formula, in a 1:1 ratio, for 8 weeks. Study visits will be conducted every 4 weeks during the treatment period.

OTHER

Thickened formula

This will be a randomised, single blind, controlled, multicenter study, designed to evaluate efficacy and safety of Zinc-L carnosine/Polaprezinc in infants (1-12 months of age) with symptoms suggestive of GER. This study will include a 2-week screening period, and a 8-week treatment period. After the screeing phase, eligible patients will be randomly assigned to either Zinc-L carnosine/Polaprezinc (Hepilor Liquido, Azienda Farmaceutica Italiana, Italy) twice a day or thickened formula, in a 1:1 ratio, for 8 weeks. Study visits will be conducted every 4 weeks during the treatment period.

All Listed Sponsors
collaborator

Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria

OTHER

lead

University of Roma La Sapienza

OTHER

NCT06678997 - Polaprezinc (Zinc L-carnosine) in Infants With Gastroesophageal Reflux | Biotech Hunter | Biotech Hunter