Effect of Intranasal Oxytocin on Emotion Recognition and Acute Psycho-Social Stress-induced Cortisol Increase in Patients With Central Diabetes Insipidus and Healthy Controls

PHASE2RecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

May 16, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

February 28, 2027

Conditions
Arginine Vasopressin DeficiencyDiabetes Insipidus
Interventions
DRUG

Oxytocin nasal spray

Participants will be instructed on correctly applying the intranasal study medication and will self-administer a single dose of 24 IU oxytocin under the supervision of unblinded study personnel.

OTHER

Placebo

Participants will be instructed on correctly applying the intranasal study medication and will self-administer a single dose of placebo (0.9% normal saline) under the supervision of unblinded study personnel.

Trial Locations (1)

4031

RECRUITING

University Hospital Basel, Basel

All Listed Sponsors
lead

University Hospital, Basel, Switzerland

OTHER