INtraprocedural Feedback-Optimized Renal Denervation Based on Measurements Obtained Through Renal Artery Stimulation: a Randomized Controlled Trial (INFORM)

PHASE4RecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

October 14, 2024

Primary Completion Date

October 31, 2026

Study Completion Date

June 30, 2028

Conditions
Hypertension, UncontrolledHypertension, ResistantHypertension
Interventions
DEVICE

Radiofrequency ablation alone, re-denervation to main and/or branch renal artery

Re-denervation according to the site where renal artery stimulation can induce systolic blood pressure rise of \>= 20 mmHg. Main renal artery denervation if proximal main renal artery stimulation positive, while branch renal artery denervation if distal main renal artery stimulation positive.

PROCEDURE

Radiofrequency ablation alone, no further renal denervation

No further renal denervation after standard renal denervation even renal artery stimulation-induced systolic blood pressure rise \>= 20 mmHg

Trial Locations (1)

100225

RECRUITING

National Taiwan University Hospital, Taipei

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Smart Health Technology Research and Development Center, National Taiwan University

UNKNOWN

collaborator

Medtronic

INDUSTRY

lead

National Taiwan University Hospital

OTHER

NCT06676553 - INtraprocedural Feedback-Optimized Renal Denervation Based on Measurements Obtained Through Renal Artery Stimulation: a Randomized Controlled Trial (INFORM) | Biotech Hunter | Biotech Hunter