Pembrolizumab Plus Lenvatinib in Unresectable Cutaneous Angiosarcoma Patients

PHASE2RecruitingINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

November 30, 2028

Study Completion Date

November 30, 2029

Conditions
Angiosarcoma of SkinAngiosarcoma Metastatic
Interventions
DRUG

Pembrolizumab plus Lenvatinib

"One course is fixed at 21 days, and the length of course is not extended or shortened.~Participants receive 200 mg of pembrolizumab injection intravenously over approximately 30 minutes on day 1 of each course, and take 20 mg of lenvatinib capsules orally once daily, preferably at the same time each day.~Treatment with pembrolizumab and lenvatinib will be continued for up to 35 courses unless the criteria for termination of protocol treatment are met."

Trial Locations (5)

Unknown

RECRUITING

National Cancer Center Hospital East, Kashiwa

RECRUITING

University Hospital Kyoto Prefectural University of Medicine, Kyoto

RECRUITING

Nagoya City University Hospital, Nagoya

RECRUITING

Keio University Hospital, Tokyo

RECRUITING

National Cancer Center Hospital, Tokyo

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

National Cancer Center, Japan

OTHER_GOV