430
Participants
Start Date
December 1, 2024
Primary Completion Date
November 30, 2029
Study Completion Date
November 30, 2029
TBICy
The TBI-Cy group was administered 250 mg/m2/d oral Me-CCNU on day -8. A total of 12 Gy TBI was for each patient and fractionated dose was 2 Gy twice daily or 4Gy once daily on days -8 to -6. Occluding of the lung fields during TBI, the corresponding irradiation dose reduced to a total of 8 Gy. On day -5, the schedule was intravenous 2 g/m2 Ara-C every 12 hours. Then intravenous 1.8 g/m2 CTX once per day from days -4 to -3.
BuCy
The BuCy group received oral Me-CCNU 250 mg/m2/d twice daily on day -8, intravenous cytosine arabinoside (Ara-C) 2 g/m2 twice daily on day -7, intravenous Bu 3.2 mg/kg/d from days -6 to -4, and intravenous cyclophosphamide (CTX) 1.8 g/m2/d from days -3 to -2. There were no patients accepted oral Bu.
The First Affiliated Hospital of Soochow University, Suzhou
Children's Hospital of Soochow University
OTHER
Ruijin Hospital
OTHER
Nanfang Hospital, Southern Medical University
OTHER
Fujian Medical University Union Hospital
OTHER
First Affiliated Hospital Xi'an Jiaotong University
OTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
Zhejiang University
OTHER
Anhui Provincial Hospital
OTHER_GOV
The First Affiliated Hospital of Soochow University
OTHER