Tolerance and Effectiveness of C14 on HPV Infection

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

November 15, 2024

Primary Completion Date

March 15, 2025

Study Completion Date

July 15, 2025

Conditions
HPV-induced CancersHPV InfectionsHIVCervical CancersTrialC14Monoterpenoid Zinc Tetra-ascorbo-camphorate
Interventions
DRUG

"The monoterpenoid zinc tetra-ascorbo-camphorate (C14)"

The trial phase will consist of hospital administration by vaginal syringe of 5ml of 1% C14, twice a day for 7 days, starting the first cure during the follicular phase of the cycle, just after the last menstrual period (S1), the second cure the following month (S5), the third cure 4 weeks later (S9) and the last cure 8 weeks later (S13). Gynaecological follow-up with HPV molecular testing and cervical smear will be performed two days after each course of treatment at S2, S6, S10, S14 and 2 weeks after the last course of treatment (S16). Unprotected sexual intercourse will not be permitted during each course of treatment, and for at least 72 hours before each genital swab.

DRUG

Distilled water group

Instead of C14, distilled water will be administered in this group.

Trial Locations (1)

Unknown

Polyclinique Citadelle, Bunia

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MGB Pharma

INDUSTRY

NCT06672653 - Tolerance and Effectiveness of C14 on HPV Infection | Biotech Hunter | Biotech Hunter