The CardioMEMS Vericiguat Heart Failure Trial

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

December 1, 2024

Study Completion Date

January 31, 2026

Conditions
Heart FailurePulmonary Arterial Hypertension
Interventions
DRUG

Vericiguat

Participants will receive vericiguat and placebo with a cross-over intermediate wash-out period. Patients will randomly be allocated 1:1 to two 6-week treatment sequences: either vericiguat first then placebo, or vice versa. The study drug dose will be doubled every 2 weeks (e.g., 2.5, 5, and 10 mg)

DRUG

Placebo

Participants will receive vericiguat and placebo with a cross-over intermediate wash-out period. Patients will randomly be allocated 1:1 to two 6-week treatment sequences: either vericiguat first then placebo, or vice versa. The study drug dose will be doubled every 2 weeks (e.g., 2.5, 5, and 10 mg)

All Listed Sponsors
collaborator

Aarhus University Hospital

OTHER

lead

Finn Gustafsson

OTHER

NCT06671990 - The CardioMEMS Vericiguat Heart Failure Trial | Biotech Hunter | Biotech Hunter