Nab-TPC vs GP Combined With Camrelizumab in the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma

PHASE3RecruitingINTERVENTIONAL
Enrollment

242

Participants

Timeline

Start Date

November 27, 2024

Primary Completion Date

November 20, 2027

Study Completion Date

November 20, 2029

Conditions
Nasopharyngeal Cancinoma (NPC)
Interventions
DRUG

Camrelizumab combined GP chemotherapy

Camrelizumab was intravenously given at dose of 200 mg on day 1. The GP regimen included gemcitabine administered at a dose of 1 g/m2 on day 1 and day 8, cisplatin at a dose of 80 mg/m2 on day 1.Q3W 1 cycle, 4-6 cycles.

DRUG

Camrelizumab combined TPC chemotherapy

Camrelizumab was intravenously given at dose of 200 mg on day 1. The TPC regimen included nab-paclitaxel administered at a dose of 200 mg/m2 on day 1, cisplatin at a dose of 60 mg/m2 on day 1, and capecitabine at a dose of 1000 mg/m2, taken orally twice a day on days 1 to 14, for each cycle. Q3W 1 cycle, 4-6 cycles.

Trial Locations (1)

510060

RECRUITING

SunYat-senU, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER