A Mouthwash Medicine for the Reduction or Prevention of Mouth Ulceration Caused by Radiotherapy for Head and Neck Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

May 22, 2023

Primary Completion Date

August 20, 2024

Study Completion Date

August 20, 2024

Conditions
Oral Mucositis
Interventions
DRUG

NG11-2

"NG11-2 dose level will vary from 0.92 mg/mL to 5.5 mg/mL during the dose escalation process. The NG11-2 is given as an oral rinse.~Throughout the radiotherapy regimen, no more than 60 minutes prior to the completion of radiotherapy, on each weekday the patient will rinse their mouth with 12.5 ml of NG11-2 for between 90 \& 120 seconds duration, gargling twice for approximately three seconds each if possible during this period then expectorate the solution."

Trial Locations (4)

AB25 2ZN

Aberdeen Royal Infirmary, Aberdeen

BT9 7AB

Belfast City Hospital, Belfast

B15 2TH

Queen Elizabeth Hospital, Birmingham

SE1 9RT

Guy's & St Thomas' Hospital, London

All Listed Sponsors
lead

VasoDynamics Ltd

INDUSTRY

NCT06669390 - A Mouthwash Medicine for the Reduction or Prevention of Mouth Ulceration Caused by Radiotherapy for Head and Neck Cancer | Biotech Hunter | Biotech Hunter