30
Participants
Start Date
February 10, 2025
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2027
Ketamine
The subjects will receive 1:1 single IV racemic ketamine (dosed @0.5 mg/kg actual body weight) (n=15) 40-min infusion in an MRI scanner, followed by an optional open-label ketamine infusion (available to everyone) 1-7 days after the initial treatment
Normal Saline
The subjects will receive 1:1 single IV normal saline/placebo (n=15) 40-min infusion in an MRI scanner, followed by an optional open-label ketamine infusion (available to everyone) 1-7 days after the initial treatment
RECRUITING
Mayo Clinic in Rochester, Rochester
Lead Sponsor
National Center for Advancing Translational Sciences (NCATS)
NIH
Mayo Clinic
OTHER