Clinical Study of Therapeutic Immunological Agent for EBV Lymphoproliferative Diseases

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
CAEBV (Chronic Active Epstein-Barr Virus Infection) SyndromePTLDs
Interventions
BIOLOGICAL

EBV immunological agent

"27 participants with will be enrolled in the study and divided into three groups, including EBV-LPD (Adults group), EBV-LPD (Children group) and PTLD (Adults group) each with 9 people.The participants will be divided into three different dose groups, and a 3+3 dose escalation design is used. The low dose is 5.0×10\^5, the medium dose is 2.0×10\^6 and the high dose is 5.0×10\^6 for children and low dose is 5.0×10\^6, the medium dose is 2.0×10\^7 and the high dose is 5.0×10\^7 for adults. Only one dose will be administered to each participant with EBV immunological agent combined with Toripalimab 240mg."

Trial Locations (1)

Unknown

West China Hospital, Chengdu

All Listed Sponsors
lead

West China Hospital

OTHER

NCT06666153 - Clinical Study of Therapeutic Immunological Agent for EBV Lymphoproliferative Diseases | Biotech Hunter | Biotech Hunter