The Study of CYP2C19 Genotype-Guided Clopidogrel Treatment Models

NACompletedINTERVENTIONAL
Enrollment

283

Participants

Timeline

Start Date

June 15, 2023

Primary Completion Date

May 15, 2025

Study Completion Date

July 5, 2025

Conditions
Coronary Artery DiseaseClopidogrel ResistanceCoronary ThrombosisAdverse Cardiac EventsBleedingHospitalisationsDeathDeath From Cardiovascular Disease
Interventions
OTHER

CYP2C19 Genotype-Guided Clopidogrel Treatment

Clopidogrel as a component of preventive antiplatelet treatment such as double antiplatelet treatment (DAPT), or an antiplatelet drug (clopidogrel) combined with the non-vitamin K antagonist oral anticoagulants (NOAC), incl. triple antiplatelet treatment (Aspirin, Clopidogrel and a NOAC), or antiplatelet monotherapy (Clopidogrel).

OTHER

CYP2C19 Genotype Guided Antiplatelet Treatment Alternative to Clopidogrel

An antiplatelet drug alternative to clopidogrel in conventional dosing regimen, as a component of preventive antiplatelet treatment, such as double antiplatelet treatment (DAPT) with ticagrelor or prasugrel, or prasugrel combined with the non-vitamin K antagonist oral anticoagulants (NOAC), or antiplatelet monotherapy (ticagrelor, or prasugrel).

OTHER

The Conventional Clopidogrel Treatment

Clopidogrel as a component of preventive antiplatelet treatment such as double antiplatelet treatment (DAPT), or clopidogrel combined with the non-vitamin K antagonist oral anticoagulants (NOAC), incl. triple antiplatelet treatment (Aspirin, Clopidogrel and a NOAC), or antiplatelet monotherapy (Clopidogrel).

Trial Locations (4)

Unknown

1st University Clinic of the Tbilisi State Medical University, Tbilisi

Cardio Expert Ltd., Clinic Cardio, Tbilisi

T. Oragvelidze Cardiology Center, Tbilisi

Tbilisi Institute of Medicine, Tbilisi

All Listed Sponsors
collaborator

Tbilisi State Medical University

OTHER

lead

Vistamedi Ltd.

INDUSTRY

NCT06665919 - The Study of CYP2C19 Genotype-Guided Clopidogrel Treatment Models | Biotech Hunter | Biotech Hunter