G-Pola-ZLP in Diffuse Large B-Cell Lymphoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

September 24, 2025

Primary Completion Date

January 31, 2029

Study Completion Date

January 31, 2030

Conditions
Diffuse Large B-Cell Lymphoma
Interventions
DRUG

Glofitamab, Polatuzumab Vedotin, Zanubrutinib, Lenalidomide and Prednisone as Induction Therapy

Patients were treated by Glofitama(Cycle 1: D8, 2.5mg, D15, 10mg; followed by the target dose of 30mg on D1 of Cycle 2-12), Polatuzumab Vedotin(1.8mg/kg iv qd d1), Zanubrutinib(160mg po bid d1-21), Lenalidomide(25mg po qd d1-14) and Prednisone(60mg/m2 po qd d1-5) as induction therapy.

All Listed Sponsors
lead

Navy General Hospital, Beijing

OTHER

NCT06665217 - G-Pola-ZLP in Diffuse Large B-Cell Lymphoma | Biotech Hunter | Biotech Hunter