Comparison of Weight Loss and Nutritional Deficiency After One Anastomosis Gastric Bypass at 150, 170, and 200 cm From the Duodenojejunal Junction

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 20, 2023

Primary Completion Date

June 20, 2024

Study Completion Date

June 20, 2024

Conditions
ObesityNutritional DeficiencyType 2 Diabetes Mellitus (T2DM)Bariatric Surgery (Gastric Bypass)
Interventions
PROCEDURE

One Anastomosis Gastric Bypass (150 cm from Duodenojejunal Junction)

This intervention involves performing a One Anastomosis Gastric Bypass surgery with the bypassed length of the small intestine set at 150 centimeters from the duodenojejunal junction. This shorter limb length is designed to achieve weight loss while potentially reducing the risk of nutritional deficiencies. The procedure is performed laparoscopically, with the stomach divided to create a gastric tube attached to a loop of the small intestine. Postoperative outcomes will include assessments of weight loss, total weight loss percentage, excess weight loss percentage, and nutritional markers such as albumin, calcium, and iron.

PROCEDURE

One Anastomosis Gastric Bypass (170 cm from Duodenojejunal Junction)

This intervention involves performing a One Anastomosis Gastric Bypass surgery with a bypassed length of 170 centimeters from the duodenojejunal junction, offering an intermediate limb length. This distance is intended to balance weight loss effectiveness with moderate risks of nutritional deficiencies. The laparoscopic procedure involves creating a gastric tube attached to a segment of the small intestine, bypassing the proximal portion. Outcomes monitored postoperatively include weight loss, percentage of total and excess weight loss, and nutritional parameters such as albumin, calcium, and iron levels.

PROCEDURE

One Anastomosis Gastric Bypass (200 cm from Duodenojejunal Junction)

This intervention consists of performing a One Anastomosis Gastric Bypass with the bypass length set at 200 centimeters from the duodenojejunal junction. This longer bypass length is designed to maximize weight loss outcomes but may carry a higher risk of nutritional deficiencies. The procedure is done laparoscopically, where the stomach is divided, creating a tube that is joined to the small intestine at the specified length. Postoperative assessments will focus on weight loss effectiveness, total and excess weight loss percentages, and the risk of nutritional deficiencies by measuring markers such as albumin, calcium, and iron.

Trial Locations (1)

11511

Cairo University Hospitals, Cairo

All Listed Sponsors
lead

Cairo University

OTHER