24
Participants
Start Date
November 1, 2024
Primary Completion Date
January 1, 2030
Study Completion Date
January 1, 2030
Replacement of the esophagus with a decellularized human esophagus graft
The Decellularized Human Esophagus (DHE) will be surgically implanted under general anesthesia via right or left thoracotomy or cervicotomy, depending on the location of the stenosis, to replace the esophageal defect created by resection of the stenosis. An omentoplasty is performed laparoscopically beforehand to provide secondary coverage of the graft area. A temporary esophageal stent is placed endoscopically to cover the DHE and the two anastomoses for a period of 3 months, to prevent the development of an anastomotic fistula and stenosis of the graft area.
Assistance Publique - Hôpitaux de Paris
OTHER