Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 9, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2027

Conditions
Alzheimer Disease
Interventions
OTHER

Basal tear collection for the analysis of metabo-lipidomic profiles and concentrations of protein biomarkers (Tau, phosphorylated Tau, Aβ 1-40, and Aβ 1-42)

Collection of a tear volume of (i) 2 x 5µL using glass microcapillary tubes and (ii) 12µL using Schirmer strips after the instillation of anesthetic eye drops for metabo-lipidomic analysis and multiplexing of protein markers

OTHER

Collection of a blood sample (5 mL) for blood biomarkers analysis

Collection of a blood sample (5 mL) for blood biomarkers analysis.

Trial Locations (1)

37044

RECRUITING

CHRU de Tours, Tours

All Listed Sponsors
lead

University Hospital, Tours

OTHER

NCT06661564 - Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study | Biotech Hunter | Biotech Hunter