150
Participants
Start Date
September 1, 2025
Primary Completion Date
September 1, 2027
Study Completion Date
September 1, 2027
Cyclosporine A
Participants with smear or culture proven fungal keratitis are treated for a minimum of 48 hours with topical natamycin and then randomized in a 1:1:1 ratio to receive either topical Cyclosporine A (CsA) 0.1%, 2% or placebo for 4 weeks. Natamycin is continued until the ulcer has healed.
Placebo Comparator: Placebo
Participants with smear or culture proven fungal keratitis are treated for a minimum of 48 hours with topical natamycin and then randomized in a 1:1:1 ratio to receive either topical Cyclosporine A (CsA) 0.1%, 2% or placebo for 4 weeks. Natamycin is continued until the ulcer has healed.
NOT_YET_RECRUITING
University of California, San Farncisco, San Francisco
RECRUITING
Aravind Eye Institute, Pondicherry
Aravind Eye Hospitals, India
OTHER
Aravind Eye Care System
OTHER
University of California, San Francisco
OTHER