15
Participants
Start Date
October 10, 2024
Primary Completion Date
December 30, 2025
Study Completion Date
October 30, 2026
Telitacicept 160mg
Telitacicept for Injection combined with standard therapy (Prednisone and Cyclophosphamide) for the treatment of ANCA-associated nephritis (AAGN).
Prednisone (and methylprednisolone)
Methylprednisone shock therapy (500mg, 3 times), followed by Prednisone (1 mg·kg·d and a pre-determined tapering guideline \[PEXIVAS regimen\]).
Cyclophosphamide
Cyclophosphamide, intravenous injection, once every 2 to 3 weeks, 0.75 g/m² each time, the maximum cumulative dose of 8g
Renmin hospital of Wuhan University, Wuhan
Renmin Hospital of Wuhan University
OTHER