Combination of TURP and Standard Systemic Therapy for MPCa

PHASE2RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

September 21, 2024

Primary Completion Date

September 30, 2026

Study Completion Date

December 31, 2026

Conditions
Metastatic Prostate Cancer
Interventions
PROCEDURE

TURP

Participants will undergo Transurethral Resection of the Prostate (TURP), a surgical procedure performed to relieve symptoms of urinary obstruction caused by the prostate tumor

DRUG

Standard Medical Therapy

Participants will receive Standard Medical Therapy, which includes ADT, typically with an LHRH agonist or antagonist, to reduce testosterone levels, a key driver of prostate cancer progression. In addition to ADT, participants may be treated with second-generation anti-androgen drugs such as Abiraterone or Enzalutamide. These medications block androgen receptor signaling and further inhibit the cancer\'s ability to grow.

Trial Locations (1)

200032

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER