Neoadjuvant Camrelizumab With Palbociclib for Resectable Esophageal Squamous Cell Carcinomas

PHASE1RecruitingINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

August 4, 2024

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
DRUG

Camrelizumab

Camrelizumab will be given at at a dose of 200 mg intravenously on day 23 of a planned 28-day cycle, and two doses before surgery.

DRUG

Palbociclib(100mg)

Palbociclib will be given at a dose of 100 mg every day orally with three weeks on and one week off. Four weeks is a cycle and it will be given for three cycles.

DRUG

Palbociclib(125mg)

Palbociclib will be given at a dose of 125 mg every day orally with three weeks on and one week off. Four weeks is a cycle and it will be given for three cycles.

Trial Locations (1)

610041

RECRUITING

West China Hospital, Sichuan University, Chengdu

All Listed Sponsors
lead

West China Hospital

OTHER