12
Participants
Start Date
January 1, 2023
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2029
Dabrafenib
"Dosage: 150 mg orally, twice daily (total daily dose of 300 mg) Administration: Administer at approximately 12 hours apart. Take at the same time each day. If a dose is missed and less than 6 hours remain until the next dose, skip the missed dose. Do not open, crush, or break the capsules.~Usage in Combination: When used in combination with trametinib, trametinib should be taken once daily at the same time as either the morning or evening dose of dabrafenib to ensure synchronization of the treatment schedule."
Trametinib
"Dosage: 2 mg orally, once daily Administration: Administer at least 1 hour before or 2 hours after a meal. Take at the same time each day. If a dose is missed, it should be taken no later than 12 hours before the next scheduled dose; otherwise, skip the missed dose.~Usage in Combination: When used in combination with trametinib, trametinib should be taken once daily at the same time as either the morning or evening dose of dabrafenib to ensure synchronization of the treatment schedule."
RECRUITING
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
OTHER