Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

November 18, 2024

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2027

Conditions
Hepatocellular Carcinoma (HCC)
Interventions
BIOLOGICAL

SN301A

"SN301A is an investigational off-the-shelf CAR NK cell therapy, armed with calibrated release (cr)IL15, designed to selectively target and treat GPC3 expressing advanced hepatocellular carcinoma.~Subjects will receive lymphodepletion pretreatment (Fludarabine/Cyclophosphamide), three SN301A intravenous infusions in a cycle (D0, D7, D14), with each subject receiving a maximum of 3 cycles."

Trial Locations (1)

200080

RECRUITING

Shanghai General Hospital, Shanghai

All Listed Sponsors
collaborator

Celest Therapeutics Co. Ltd

UNKNOWN

collaborator

Senti Biosciences

INDUSTRY

lead

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

NCT06652243 - Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma | Biotech Hunter | Biotech Hunter