CCTA to Optimize Diagnostic Yield of Invasive Angiography With AI

NARecruitingINTERVENTIONAL
Enrollment

252

Participants

Timeline

Start Date

January 9, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Coronary Artery Disease
Interventions
OTHER

Usual Care

In the usual care group, patients will proceed directly to ICA following referral from community cardiology, as is the current standard of care. Research staff will screen participants in this group for significant CAD using the decision support tool; however, the tool's recommendations will not affect their care, as all patients in this group will invariably receive ICA.

OTHER

Centralized triage with risk score-based screening for obstructive CAD

Patients randomized to the intervention will have selected features of their medical history, recorded on their referral form, entered into a decision support tool by research personnel to generate a recommendation of whether they should proceed directly to ICA or whether they should receive CCTA. Patients with recommendations for ICA will proceed directly to ICA. Patients with recommendations for CCTA will be referred to CCTA. Based on the results of the CCTA, recommendations for medical management versus referral for ICA will be made.

Trial Locations (3)

L8L 2X2

RECRUITING

Hamilton General Hospital, Hamilton

L8N 3Z5

NOT_YET_RECRUITING

McMaster University Medical Centre, Hamilton

L2S 0A9

NOT_YET_RECRUITING

St. Catharines Hospital, St. Catharines

Sponsors
All Listed Sponsors
collaborator

Population Health Research Institute

OTHER

collaborator

Hamilton Academic Health Sciences Organization

OTHER

lead

Hamilton Health Sciences Corporation

OTHER

NCT06648239 - CCTA to Optimize Diagnostic Yield of Invasive Angiography With AI | Biotech Hunter | Biotech Hunter