Zanubrutinib Plus Rituximab As Front-line Treatment for Mucosa-associated Lymphoid Tissue Lymphoma (MALT)

PHASE2RecruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

October 30, 2024

Primary Completion Date

August 31, 2028

Study Completion Date

September 30, 2028

Conditions
Mucosa-associated Lymphoid Tissue Lymphoma (MALT)
Interventions
DRUG

Zanubrutinib

160 mg, administered twice daily from Day 1 to Day 28 (D1-D28)

DRUG

Rituximab

375 mg/m², administered once a week during Cycle 1 (C1), and on Day 1 (D1) of Cycles 2-6 (C2-C6)

Trial Locations (1)

51000

RECRUITING

Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University, Guangzhou

All Listed Sponsors
collaborator

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Gansu Cancer Hospital

OTHER

collaborator

Fifth Affiliated Hospital of Guangzhou Medical University

OTHER

collaborator

Beijing Tongren Hospital

OTHER

collaborator

Tongji Medical College of Huazhong University of Science & Technology

UNKNOWN

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

Shenzhen People's Hospital

OTHER

lead

Sun Yat-sen University

OTHER