Study of the Efficacy, Safety, Pharmacokinetics, and Immunogenicity of Netakimab in Children With Moderate to Severe Plaque Psoriasis

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

August 8, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

February 29, 2028

Conditions
Plaque Psoriasis
Interventions
DRUG

Netakimab

netakimab will be administered subcutaneously with induction once a week for the first three weeks, then once every 4 weeks

DRUG

Placebo

placebo will be administered subcutaneously at a scheme masking netakimab treatment

DRUG

Adalimumab

adalimumab will be administered subcutaneously at weeks 1, 2, and then once every 2 weeks

Trial Locations (14)

Unknown

"Federal State Budgetary Educational Institution of Higher Education Altai State Medical University of the Ministry of Health of the Russian Federation", Barnaul

"State budgetary healthcare institution Chelyabinsk Regional Clinical Dermatovenerological Dispensary", Chelyabinsk

"Limited Liability Company Health Azbuka Medical Center", Kazan'

"State Autonomous Healthcare Institution Republic Clinical Dermatovenerologic Dispensary of the Ministry of Health of the Republic of Tatarstan named after Professor Ge", Kazan'

"State Autonomous Healthcare Institution Kuzbass Clinical Dermatovenerological Dispensary", Kemerovo

"Federal State Budgetary Educational Institution of Higher Education Kirov State Medical University of the Ministry of Health of the Russian Federation", Kirov

"State budgetary healthcare institution Clinical Dermatovenerologic Dispensary of the Ministry of Health of the Krasnodar Territory", Krasnodar

"Federal State Autonomous Institution National Medical Research Center for Children's Health of the Ministry of Health of the Russian Federation", Moscow

"Federal State Budgetary Institution State scientific centre of dermatovenerology and cosmetology of the Ministry of health of Russian Federation, Nizhny Novgorod branch", Nizhny Novgorod

"Federal State Budgetary Educational Institution of Higher Education St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation", Saint Petersburg

"Limited Liability Company PiterKlinika", Saint Petersburg

"Federal State Budgetary Educational Institution of Higher Education Siberian State Medical University of the Ministry of Health of the Russian Federation", Tomsk

"Federal State Budgetary Educational Institution of Higher Education Siberian State Medical University", Tomsk

"State budgetary institution of the Sverdlovsk region Ural Research Institute of Dermatovenereology and Immunopathology", Yekaterinburg

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biocad

INDUSTRY

NCT06640517 - Study of the Efficacy, Safety, Pharmacokinetics, and Immunogenicity of Netakimab in Children With Moderate to Severe Plaque Psoriasis | Biotech Hunter | Biotech Hunter