NCT06629077View on ClinicalTrials.gov

Brain Blood Vessel Responses to Changes in Blood Flow

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Magnetic Resonance ImagingCerebrovascular Circulation
Interventions
DEVICE

MRI

Participants will undergo an MRI scan while performing breathing and a simulated postural change task.

DRUG

Prazosin

A dose of prazosin will be administered based on body weight.

DRUG

Placebo

Oral placebo

Trial Locations (1)

53705

University of Wisconsin, Madison

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

University of Wisconsin, Madison

OTHER