A Study of CT-388 in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

360

Participants

Timeline

Start Date

November 21, 2024

Primary Completion Date

August 10, 2026

Study Completion Date

November 30, 2026

Conditions
Overweight or ObeseType 2 Diabetes Mellitus (T2DM)
Interventions
DRUG

Placebo

Placebo will be volume-matched and administered subcutaneously (SC) once weekly.

DRUG

CT-388

CT-388 will be administered subcutaneously (SC) once weekly at the randomized dosing regimen.

Trial Locations (70)

1010

Optimal Clinical Trials, Grafton

1120

Centro Medico Viamonte SRL, Buenos Aires

2120

Momentum Pukekohe, Auckland

3110

Tauranga Hospital, Tauranga

6021

Momentum Wellington, Wellington

11215

Ellipsis Research Group, Brooklyn

20110

Manassas Clinical Research Center, Manassas

20715

Flourish Research Acquisition, LLC dba Flourish Bowie, Bowie

21075

Centennial Medical Group, Elkridge

21200

Centro De Investigacion En Artritis Y Osteopososis, Mexicali

27103

Accellacare Research of Winston Salem, Winston-Salem

27518

Accellacare of Cary, Cary

27804

Accellacare of Rocky Mount, Rocky Mount

28401

Accellacare of Wilmington, LLC, Wilmington

28601

Accellacare - Hickory, Hickory

28625

Accellacare of Piedmont Healthcare, Statesville

29464

Roper St. Francis Physician Partners - Primary Care, Mt. Pleasant

30214

Privia Medical Group Georgia, LLC, Fayetteville

30291

Rophe Adult and Pediatric Medicine/SKYCRNG, Union City

31792

Privia Medical Group Georgia - Thomasville, Thomasville

32159

K2 Summit Research, The Villages

32751

K2 Medical Research, LLC - Maitland, Maitland

K2 Medical Research, LLC - Orlando, Maitland

32806

K2 Medical Research, LLC - South Orlando, Orlando

33138

Flourish Research Acquisition, LLC, Miami

33434

Flourish Research - Boca Raton, Boca Raton

33607

K2 Medical Research Tampa, Tampa

33713

Aging Well Associates, St. Petersburg

33761

Tampa Bay Medical Research, Clearwater

35233

University of Alabama at Birmingham (UAB), Birmingham

35976

Lakeview Clinical Research, LLC, Guntersville

37912

Norwood Family Medicine, Knoxville

37938

Summit-Halls Family Practice, Knoxville

38654

Olive Branch Family Medical Center; Family Medicine, Olive Branch

39157

SKY Integrative Medical Center/SKYCRNG, Ridgeland

44718

Diabetes and Endocrinology Associates of Stark County, Inc., Canton

50010

McFarland Clinic, Ames

60148

Duly Health and Care, Lombard

62250

Instituto de Diabetes Obesidad y Nutricion, SC, Cuernavaca

66260

Avant Santé Research Center, San Pedro Garza García

66606

Cotton O'Neil Clinical Research Center, Topeka

68198

University of Nebraska Medical Center, Omaha

70006

NOLA Cares, LLC, Metairie

73013

Tekton Research, Edmond

75230

Velocity Clinical Research - Dallas, Dallas

75390

University of Texas Southwestern Medical Center Investigation Drug Services, Dallas

76401

Privia Medical Group North Texas - Stephenville, Stephenville

77040

Juno Research, LLC, Houston

78231

Consano Clinical Research, Shavano Park

78731

FutureSearch Trials of Neurology, Austin

80230

SINACOR, Culiacán

85364

Yuma Clinical Trials, Yuma

90806

Ark Clinical Research, Long Beach

91403

Asclepes Research Centers, Sherman Oaks

91763

Catalina Research Institute, LLC, Montclair

91855

Sociedad de Metabolismo y Corazon S.C., Veracruz

91900

FAICIC S de R.L. de C.V, Veracruz

91978

Encompass Clinical Research, Spring Valley

92025

AMCR Institute, Escondido

92630

Orange Country Research Center, Lake Forest

92708

Ark Clinical-Fountain Valley, Fountain Valley

97070

Medical Care and Research S.A de C.V, Mérida

35209-8401

Central Alabama Research, Birmingham

02721

NECCR PrimaCare Research LLC, Fall River

L6S 0C6

Centricity Research Brampton Endocrinology, Brampton

L6T 0G1

Aggarwal and Associates, Brampton

06100

CEMDEC S.A. de C.V., Cuauhtémoc

03300

Clinicos Asociados Bocm, S.C., Mexico City

0632

Optimal Clinical Trials - North, Rosedale

00970

ISIS Clinical Research Center, Guaynabo

Sponsors
All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Carmot Therapeutics, Inc.

INDUSTRY