Safety of Anal Curcumin

PHASE1RecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

March 17, 2025

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Anal High Grade Squamous Intraepithelial Lesion
Interventions
DRUG

Curcuminoid Capsules

"500 mg curcuminoids from C3 Complex capsule. Curcuma longa (Turmeric), a constituent of the spice turmeric, is considered a low-toxicity, dietary-derived agent with chemopreventive and therapeutic benefits Study participants will be instructed to insert the curcumin capsules gelatin intra-anally every day for a 14-day treatment period.~Escalating doses"

Trial Locations (2)

30303

RECRUITING

Grady Memorial Hospital, Atlanta

30308

RECRUITING

Grady Hospital - Ponce De Leon Clinic, Atlanta

All Listed Sponsors
lead

Lisa Flowers

OTHER