Neoadjuvant Opdualag Versus Nivolumab for Resectable High-Risk Basal Cell Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 21, 2025

Primary Completion Date

May 31, 2028

Study Completion Date

May 31, 2028

Conditions
Basal Cell Carcinoma
Interventions
DRUG

Nivolumab

Nivolumab is a fully humanized monoclonal antibody that binds to the PD-1 receptor, blocking its interactions with PD-L1 and PD-L2, and thus additionally inhibiting PD1-driven immune suppression. Nivolumab 490 mg via IV administration 28 day cycle

DRUG

Opdualag

Opdualag (Opdualag) is supplied as a single dose vial containing 240 mg of Nivolumab and 80 mg. Relatlimab per 20 mL for intravenous administration ; 28 day cycle.

Trial Locations (1)

92093

RECRUITING

University of California, San Diego Moores Cancer Center, La Jolla

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

University of California, San Diego

OTHER

NCT06624475 - Neoadjuvant Opdualag Versus Nivolumab for Resectable High-Risk Basal Cell Carcinoma | Biotech Hunter | Biotech Hunter