Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas

PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 7, 2024

Primary Completion Date

December 1, 2026

Study Completion Date

December 1, 2026

Conditions
Basal Cell Carcinoma (BCC)
Interventions
DRUG

aminolevulinic acid HCL (ALA)

Prior to ALA application, the areas will be cleaned with alcohol and debrided gently with prep tape. ALA will then be applied to each of the study lesions and allowed to incubate for 3 hours with occlusion prior to the PDT.

DEVICE

BLU-U device model 4170E

Participants will be subjected to dose illumination with blue light (BLU-U Model 4170E) at a power fluence of 20 mW/cm2 for a total time of 16 minutes and 40 seconds (1,000 seconds). This will result in a total light delivery dose of 20 J/cm2.

Trial Locations (1)

85006

RECRUITING

Medical Dermatology Specialists, Phoenix

All Listed Sponsors
lead

Nathalie Zeitouni

OTHER