A Real-world Study of Tenecteplase Versus Alteplase for Thrombolysis in Patients Within 4.5 H of Onset of Ischemic Stroke

RecruitingOBSERVATIONAL
Enrollment

6,000

Participants

Timeline

Start Date

October 26, 2024

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2026

Conditions
Stroke AcuteTenecteplaseAlteplase
Interventions
OTHER

Tenecteplase

The enrolled patients received treatment with tenecteplase (rhTNK-tPA) at a dosage of 0.25 mg/kg, up to a maximum of 25 mg, based on their clinical condition and the preferences expressed by the patients and their families.

OTHER

Alteplase

The enrolled patients received treatment with alteplase (rtPA) at a dosage of 0.9 mg/kg, up to a maximum of 90 mg, based on their clinical condition and the preferences expressed by the patients and their families.

Trial Locations (1)

300350

RECRUITING

Tianjin Huanhu Hospital, Tianjin

All Listed Sponsors
lead

Tianjin Huanhu Hospital

OTHER