A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

238

Participants

Timeline

Start Date

February 4, 2025

Primary Completion Date

December 16, 2026

Study Completion Date

August 24, 2028

Conditions
Lung CancerBreast Cancer
Interventions
DRUG

BMS-986507

Specified dose on specified days

DRUG

Osimertinib

Specified dose on specified days

DRUG

Pembrolizumab

Specified dose on specified days

DRUG

Nivolumab

Specified dose on specified days

Trial Locations (48)

2170

RECRUITING

Liverpool Hospital, Liverpool

4102

RECRUITING

Princess Alexandra Hospital, Woolloongabba

10060

NOT_YET_RECRUITING

Local Institution - 0056, Candiolo

13385

NOT_YET_RECRUITING

Local Institution - 0045, Marseille

15232

WITHDRAWN

Local Institution - 0014, Pittsburgh

15706

NOT_YET_RECRUITING

Local Institution - 0062, Santiago de Compostela

20133

NOT_YET_RECRUITING

Local Institution - 0033, Milan

28040

RECRUITING

Hospital Universitario Fundación Jiménez Díaz, Madrid

28041

RECRUITING

Hospital Universitario 12 de Octubre, Madrid

28050

RECRUITING

Hospital Universitario HM Sanchinarro, Madrid

28222

NOT_YET_RECRUITING

Local Institution - 0061, Majadahonda

29011

RECRUITING

H.R.U Málaga - Hospital General, Málaga

33076

NOT_YET_RECRUITING

Local Institution - 0043, Bordeaux

33081

NOT_YET_RECRUITING

Local Institution - 0034, Aviano

33136

RECRUITING

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami

34090

NOT_YET_RECRUITING

Local Institution - 0053, Montpellier

44195

RECRUITING

Cleveland Clinic, Cleveland

46026

NOT_YET_RECRUITING

Local Institution - 0060, Valencia

50134

NOT_YET_RECRUITING

Local Institution - 0035, Florence

52242

NOT_YET_RECRUITING

Local Institution - 0065, Iowa City

69008

NOT_YET_RECRUITING

Local Institution - 0050, Lyon

75248

NOT_YET_RECRUITING

Local Institution - 0054, Paris

75970

NOT_YET_RECRUITING

Local Institution - 0040, Paris

94800

NOT_YET_RECRUITING

Local Institution - 0041, Villejuif

97239

NOT_YET_RECRUITING

Local Institution - 0052, Portland

98104

RECRUITING

Swedish Medical Center, Seattle

7500921

NOT_YET_RECRUITING

Local Institution - 0048, Santiago

8330032

NOT_YET_RECRUITING

Local Institution - 0049, Santiago

8420383

NOT_YET_RECRUITING

Local Institution - 0047, Santiago

35294-3300

NOT_YET_RECRUITING

Local Institution - 0066, Birmingham

07601

RECRUITING

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack

T6G 1Z2

RECRUITING

Cross Cancer Institute, Edmonton

L3Y 2P9

NOT_YET_RECRUITING

Local Institution - 0064, Newmarket

K1H 8L6

WITHDRAWN

Local Institution - 0023, Ottawa

RECRUITING

The Ottawa Hospital - General Campus, Ottawa

H2X 3E4

RECRUITING

Centre Hospitalier de l'Université de Montréal, Montreal

H3T 1E2

RECRUITING

Jewish General Hospital, Montreal

06189

NOT_YET_RECRUITING

Local Institution - 0077, Nice

00168

NOT_YET_RECRUITING

Local Institution - 0032, Roma

2333 ZA

RECRUITING

Leids Universitair Medisch Centrum, Leiden

1066 CX

RECRUITING

Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL), Amsterdam

08035

RECRUITING

Hospital Universitari Vall d'Hebron, Barcelona

08907

NOT_YET_RECRUITING

Local Institution - 0058, Hospitalet

08036

WITHDRAWN

Local Institution - 0059, Barcelona

NW32QG

RECRUITING

Royal Free Hospital, London

G12 0YN

NOT_YET_RECRUITING

Local Institution - 0021, Glasgow

B15 2GW

RECRUITING

University Hospitals Birmingham NHS Foundation Trust, Birmingham

NE7 7DN

NOT_YET_RECRUITING

Local Institution - 0001, Newcastle upon Tyne

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT06618287 - A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter