218
Participants
Start Date
September 15, 2024
Primary Completion Date
October 15, 2028
Study Completion Date
December 15, 2028
Routine ECMO
Routine intraoperative venoarterial ECMO during lung transplant
On-demand ECMO
"Selective, indication-based intraoperative cardiopulmonary support. In this group, the transplant will be planned without cardiopulmonary support. intraoperative venoarterial ECMO will be used selectively based on hemodynamic and/or gas exchange abnormalities :~1. Inability to maintain adequate hemodynamics and stable perfusion despite volume resuscitation and vasopressor administration and in the absence of readily correctable cause~2. Inability to tolerate pulmonary artery clamping~3. Inadequate gas exchange despite attempts at the optimization of ventilator parameters and treatments related to respiratory mechanics and ventilation/perfusion matching~4. Inadequate exposure to the surgical field~5. The transplant team is concerned about the ability to maintain organ perfusion or ventilate with a lung protective strategy, even if the aforementioned criteria are unmet.~6. Concerns about donor lung quality and a desire to protect the implanted lung from single lung perfusion"
Univeristy of Alberta & Alberta Health Services, Edmonton
Vancouver General Hospital, Vancouver
University Health Network / Toronto General Hospiatl, Toronto
Centre Hospitalier de l'Université de Montréal, Montreal
Centre hospitalier de l'Université de Montréal (CHUM)
OTHER