A Human Challenge Study to Assess Protection of a Shigella Tetravalent Bioconjugate Vaccine

PHASE2RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 12, 2024

Primary Completion Date

February 28, 2026

Study Completion Date

July 31, 2026

Conditions
Shigellosis
Interventions
BIOLOGICAL

Shigella4V2

Shigella4V2 is a tetravalent bioconjugate vaccine

BIOLOGICAL

Placebo

Phosphate-buffered saline

Trial Locations (3)

21205

RECRUITING

Johns Hopkins Center for Immunization Research, Baltimore

30030

COMPLETED

Hope Clinic of Emory University, Atlanta

45229

RECRUITING

Cincinnati Children's Hospital Medical Center, Cincinnati

Sponsors
All Listed Sponsors
collaborator

Emory University

OTHER

collaborator

Johns Hopkins Bloomberg School of Public Health

OTHER

collaborator

Children's Hospital Medical Center, Cincinnati

OTHER

lead

LimmaTech Biologics AG

INDUSTRY