Tumor-Informed ctDNA Testing of Head & Neck Intent Treatment of Squamous Cell Carcinoma

RecruitingOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

October 9, 2024

Primary Completion Date

December 30, 2028

Study Completion Date

December 30, 2029

Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
PROCEDURE

Blood Specimen Collection

Approximately 20 mL of peripheral blood (10 mL per tube, x 3 Streck tubes) will be drawn at each time point

PROCEDURE

Tumor Tissue Collection

Formalin-fixed paraffin embedded tumor tissue samples (tissue blocks of 12 x 10 millimeter (mm) unstained slides) derived from biopsy or surgical resection will be collected at screening

OTHER

Medical Record Review

Medical records will be reviewed to collect standard of care p16 staining by immunohistochemistry and/or high-risk human papillomavirus (HPV) DNA or RNA testing that is performed as part of standard of care

Trial Locations (1)

94143

RECRUITING

University of California, San Francisco, San Francisco

All Listed Sponsors
collaborator

Haystack Oncology, Inc.

UNKNOWN

lead

University of California, San Francisco

OTHER