Proof of Concept Study to Assess Safety and Efficacy of Phage Therapy in Hip or Knee Prosthetic Joint Infections Due to Staphylococcus Aureus Treated by DAIR.

PHASE2Not yet recruitingINTERVENTIONAL

Enrollment

100

Participants

Timeline

Start Date

January 31, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

January 31, 2027

Conditions

Hip Prosthesis InfectionKnee Prosthesis Infection

Interventions

BIOLOGICAL

Anti-Staphylococcus aureus Bacteriophages (PP1493 and PP1815) intra-articular injection with 0.9% NaCl solution

Three intra-articular injections during and/or following DAIR procedure

DRUG

0.9% NaCl solution

Three intra-articular injections during and/or following DAIR procedure