" a Randomized Pilot Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation (ECMO-VA)."

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

November 15, 2024

Primary Completion Date

May 15, 2025

Study Completion Date

May 15, 2026

Conditions
Pneumonia, BacterialExtracorporeal Membrane Oxygenation
Interventions
DRUG

Amikacin

Patients included in the inhaled amikacin group will receive inhaled antibiotic therapy by nebulization of amikacin at a dose of 25 mg/kg in 1 daily dose (+/- 3 hours apart), within 6 hours of randomization and for a total duration of 5 days.

DRUG

Standard of care

Patients included in the standard of care group will not receive any nebulization. They will receive Standard care alone.

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT06602557 - " a Randomized Pilot Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation (ECMO-VA)." | Biotech Hunter | Biotech Hunter