Surgery for Relapsed Ovarian Cancer in Precision

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

June 30, 2030

Study Completion Date

June 30, 2030

Conditions
Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma
Interventions
PROCEDURE

surgery/chemotherapy

secondary cytoreductive surgery followed by 6 cycles of post-operative chemotherapy

DRUG

Iparomlimab/Tuvonralimab

Iparomlimab/tuvonralimab will be administered at a dose of 5 mg per kilogram IV every 21 days. Treatment will continue until disease progression confirmed by RECIST criteria v1.1, intolerable toxicity or withdrawal of consent.

Trial Locations (2)

Unknown

Zhongshan Hospital Fudan University, Shanghai

Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
collaborator

Shanghai Zhongshan Hospital

OTHER

collaborator

Tongji Hospital

OTHER

lead

Shanghai Gynecologic Oncology Group

OTHER_GOV