Study of Adebrelimab With Chemotherapy, Endoscopy and Sequential Chemoradiotherapy In Inoperable Esophageal Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2028

Conditions
Resectable Esophageal Squamous Cell Carcinoma
Interventions
DRUG

Adebrelimab injection

Experimental group:Adebrelimab is an innovative PD-L1 inhibitor, monotherapy can improve pathological complete response rates with tolerable safety

DRUG

Albumin-Bound Paclitaxel

Experimental group:combined with Adebrelimab(PD-L1 inhibitor),and carboplatin followed by endoscopic resection and subsequent simultaneous radiotherapy combined with albumin-bound paclitaxel and carboplatin

DRUG

Carboplatin injection

Experimental group:combined with Adebrelimab(PD-L1 inhibitor),and albumin-bound paclitaxel followed by endoscopic resection and subsequent simultaneous radiotherapy combined with albumin-bound paclitaxel and carboplatin

All Listed Sponsors
lead

Shanghai Zhongshan Hospital

OTHER

NCT06599775 - Study of Adebrelimab With Chemotherapy, Endoscopy and Sequential Chemoradiotherapy In Inoperable Esophageal Cancer | Biotech Hunter | Biotech Hunter