BCL-2 Inhibitors Combined with the HyperCVAD Regimen for Newly Diagnosed T-lymphoblastic Leukemia/lymphoma.

PHASE2RecruitingINTERVENTIONAL
Enrollment

206

Participants

Timeline

Start Date

August 7, 2024

Primary Completion Date

August 7, 2026

Study Completion Date

August 7, 2027

Conditions
Lymphoblastic Lymphoma, AdultLymphoblastic Leukemia, Acute T-cell
Interventions
DRUG

BCL-2 inhibitors combined with the HyperCVAD regimen

BCL-2 inhibitors combined with the HyperCVAD regimen for newly diagnosed adult T-ALL/LBL

OTHER

Propensity score matching historical data

Propensity score matching was conducted with historical data (matching factors included age, gender, initial LDH levels, and the presence or absence of a large mediastinal mass at diagnosis) to compare the advantages and disadvantages of the experimental regimen with previous induction treatment protocols.

Trial Locations (1)

Unknown

RECRUITING

Shanghai General Hospital, Shanghai

All Listed Sponsors
lead

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER