Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

PHASE4RecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

October 18, 2024

Primary Completion Date

June 30, 2028

Study Completion Date

June 30, 2028

Conditions
Human Immunodeficiency Virus (HIV)Smoking Cessation
Interventions
BEHAVIORAL

Motivational Interviewing (MI) Counseling

Six sessions of phone counseling over 10-12 weeks with MI counselor trained in motivational interviewing and tobacco use treatment.

BEHAVIORAL

Peer Mentoring

Eight sessions of informal counseling with an experienced peer former smoker living with HIV to model healthy behavior and provide practical advice and tips for quitting based on their lived experience.

BEHAVIORAL

Skills-based Text Messaging

NCI's 8-week text messaging smoking cessation program, smokefreeTXT.gov.

DRUG

Combination NRT

If they smoke 10 or more cigarettes per day (CPD), participants will receive 2 weeks of 21 mg patches, 2 weeks of 14 mg patches and 2 weeks of 7 mg patches; if they smoke less than 10 CPD, participants will receive 4 weeks of 14 mg patches and 2 weeks of 7 mg patches. Participants will receive either 2 or 4 mg of nicotine lozenges for a total of up to 20 lozenges per day.

Trial Locations (1)

10003

RECRUITING

New York University School of Global Public Health, New York

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

New York University

OTHER