TAVR vs. SAVR Study of VitaFlow Liberty® for Severe BAV Stenosis

NAEnrolling by invitationINTERVENTIONAL
Enrollment

452

Participants

Timeline

Start Date

September 8, 2025

Primary Completion Date

September 30, 2028

Study Completion Date

September 30, 2032

Conditions
Aortic StenosisBicuspid Aortic Valve (BAV)
Interventions
DEVICE

VitaFlow Liberty

All subjects randomized to the TAVR group will receive transcatheter aortic valve replacement (TAVR) with the study device of VitaFlow Liberty

DEVICE

Commercially available surgical bioprosthetic valve

All subjects randomized to the SAVR group will receive surgical aortic valve replacement (SAVR) with the control device of a commercially available surgical bioprosthetic valve.

Trial Locations (1)

610041

WEST CHINA Hospital of Sichuan University, Chengdu

All Listed Sponsors
collaborator

West China Hospital

OTHER

collaborator

The First Affiliated Hospital of Anhui Medical University

OTHER

collaborator

Zhejiang University

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

People's Hospital of Xinjiang Uygur Autonomous Region

OTHER

collaborator

Provincial Hospital of fuzhou University

UNKNOWN

collaborator

Yanan Hospital of Kunming City

UNKNOWN

lead

Shanghai MicroPort CardioFlow Medtech Co., Ltd.

INDUSTRY