Lymphocyte-sparing Thoracic Radiotherapy for Esophageal Squamous Cell Carcinoma

NARecruitingINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

June 30, 2024

Primary Completion Date

June 30, 2027

Study Completion Date

December 30, 2027

Conditions
Esophageal Squamous Cell Cancer
Interventions
RADIATION

lymphocyte-sparing radiotherapy

the radiotherapy regimen is 41.4Gy/23Fx. Ensure 95% coverage of the PTV (Planning Target Volume) and limit the doses to the heart, bilateral lungs, and spinal cord to meet the required dose constraints. While maintaining target coverage and traditional OAR (Organs At Risk) dose constraints, also address dose for lymphocyte-relate organs including the TVB1-12 thoracic vertebral bodies, ribs, spleen, and major thoracic blood vessels.

RADIATION

conventional radiotherapy

the radiotherapy regimen is 41.4Gy/23Fx. Ensure 95% coverage of the PTV (Planning Target Volume) and limit the doses to the heart, bilateral lungs, and spinal cord to meet the required dose constraints. do not limit dose for lymphocyte-relate organs including the TVB1-12 thoracic vertebral bodies, ribs, spleen, and major thoracic blood vessels.

Trial Locations (1)

200025

RECRUITING

Ruijin hospital, Shanghai jiaotong university school of medicine, Shanghai

All Listed Sponsors
lead

Ruijin Hospital

OTHER