Testing Combined IIT-SIT to Control Mosquito-Borne Diseases At Scale

NAActive, not recruitingINTERVENTIONAL
Enrollment

15,243

Participants

Timeline

Start Date

May 28, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

September 30, 2026

Conditions
DengueZikaChikungunya
Interventions
GENETIC

Wolbachia induced incompatible mating

The intervention will be performed by weekly release of male Aedes aegypti carrying Wolbachia (wAlbB strain) to mate with wild females, resulting in the death of their eggs for birth control. Before release, these males will be irradiated with X-rays to minimize the chance of any residual fertile female releases. The intervention will lead to Ae. aegypti population suppression or even elimination and preventing dengue transmission in release sites.

COMBINATION_PRODUCT

Standard traditional chemical mosquito control

Traditional and commonly used chemical insecticide will be applied to reduce the mosquito population

Trial Locations (1)

97160

Laboratorio para el Control Biolo´gico de Aedes aegypti (LCB-UADY), Universidad Autónoma de Yucatán, Mérida

All Listed Sponsors
collaborator

Universidad Autónoma de Yucatán

OTHER

collaborator

Emory University

OTHER

lead

Michigan State University

OTHER

NCT06595745 - Testing Combined IIT-SIT to Control Mosquito-Borne Diseases At Scale | Biotech Hunter | Biotech Hunter